Effects of Intensive Lipid Lowering and Omega-3 Fatty Acid on Composition of Coronary Atherosclerotic Plaque

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether intensive lipid lowering and Omega-3 fatty acid are effective in the treatment of coronary atherosclerotic plaque.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Samsung Medical Center
• Treatments: Atorvastatin Calcium

Criteria

Inclusion Criteria:

• Acute coronary syndrome within 48 hours of symptom onset

• Have de novo non-culprit coronary artery stenosis 20% to 70% by visual estimation

Exclusion Criteria:

• Cardiogenic shock

• ST segment elevation myocardial infarction within 1 week

• Hematologic disorder: neutropenia (neutrophil<3000/mm3), thrombocytopenia (platelet<100,000/mm3)

• Liver enzyme elevation: serum aspartate aminotransferase or alanine aminotransferase concentrations more than 3 times the upper limit of normal

• Impaired renal function with serum creatinine > 2mg/dL

• Bleeding diathesis or history of coagulopathy

• Pregnancy

• Hypersensitivity to heparin, dye, aspirin, clopidogrel, statin, or fish