Effects of High-velocity Resistance Training and Creatine Supplementation in Healthy Aging Males

• Status: Unknown status
• Trial end date: 2018-07-31
• Target enrollment: 0
• Participant gender: Male

Summary

The age-related loss of skeletal muscle mass (i.e. sarcopenia)and muscle performance (i.e. strength and power), decreases functionality and the ability to perform activities of daily living. Therefore, lifestyle interventions which may improve aging muscle health are important (i.e. resistance training and creatine supplementation). High-velocity resistance training (HVRT) has been shown to increase muscle mass and muscle performance in aging adults. Creatine (CR), a compound naturally found in red meat and seafood, has also been shown to increase muscle mass and muscle performance in aging adults. No study has examined the combined effects of HVRT and CR supplementation in aging adults. This study may determine whether this lifestyle intervention is effective to combat sarcopenia.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Regina

Criteria

Inclusion Criteria:

• Males (≥ 50 years) who are not engaged in supervised resistance training for ≥ 6 weeks prior to the start of the study will be recruited to participate.

Exclusion Criteria:

• Participants will be excluded if they have taken medications that affect muscle biology or creatine monohydrate ≤ 12 weeks prior to the start of the study

• If they have a history of fragility fractures; diseases that are known to affect muscle biology (i.e. corticoids)

• If they suffer from severe osteoarthritis

• If they are currently participating in moderate-vigorous resistance training (≥ 3 times per week)

• If they are vegetarian

• If they are planning to travel during the study period for greater than 2 weeks duration at a time.

• Participants with kidney or liver abnormalities will be excluded.