Overview

Effects of High-dose Dual Therapy and Bismuth Quadruple Therapy for Helicobacter Pylori Eradication on Intestinal Microecology

Status:
Recruiting

Trial end date:
2024-03-10

Target enrollment:

Participant gender:

Summary

This study was conducted to investigate the effects of high-dose diphtherapy and bismuth quadruple therapy on H. pylori eradication on intestinal microecology, to clarify the changes in intestinal microbiota diversity and structure before and after the two treatment regimens, and to explore the relationship between different treatment regimens and intestinal microbiota dysbiosis; to further guide the safety and drug resistance of H. pylori eradication by the two treatment regimens. The expected results are to observe the changes of intestinal microbiota diversity and structure before and after treatment with the two treatment regimens.

Phase:

Phase 4

Details

Lead Sponsor:

Xijing Hospital of Digestive Diseases

Treatments:

Amoxicillin
Bismuth
Clarithromycin
Esomeprazole