Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch
Status:
Completed
Trial end date:
2016-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this project is to investigate the effect of capsaicin-induced neurogenic
inflammation with three different intensities on itch subsequently induced by histamine and
cowhage. The hypothesis is that capsaicin-induced pre-established neurogenic inflammation
significantly increases susceptibility to itch provocations with cowhage and histamine.