Effects of Heart Rate Reduction on Central Arterial Pressure in Healthy Individuals
Status:
Terminated
Trial end date:
2011-11-08
Target enrollment:
Participant gender:
Summary
The purpose of this project is to determine the effects of slowing heart rate upon both
central and peripheral blood pressures using Ivabradine. The effects of Ivabradine will be
compared to Metoprolol and placebo.
Participants will attend the hospital for 3 visits where they will be randomised to receive
either Ivabradine, Metoprolol and placebo on each visit. Non-invasive measures of blood
pressure will be recorded before and after consuming the study drug.