Effects of HMG-coA Reductase Inhibitor on Rheumatoid Arthritis
Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is:
1. To evaluate the prevalence of preclinical atherosclerosis in Chinese patients with RA
compared to healthy controls.
2. To determine those clinical and biological measures that best predict the presence of
plaque and increased arterial stiffness.
3. To ascertain the efficacy and safety of rosuvastatin in the prevention of
atherosclerosis in patients with RA measured by carotid intima-media thickness (IMT) and
pulse wave velocity (PWV).