Effects of Garlic Supplements on Opioids in Healthy Volunteers
Status:
Completed
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Garlic supplements may alter the pharmacokinetics of oxycodone, thereby affecting
its effectiveness as an opioid analgesic for the relief of moderate or severe pain.
PURPOSE: This randomized phase 4 trial is studying how garlic supplements may change the
pharmacokinetics of oxycodone and its analgesic and side effects in healthy volunteers.