Effects of GH on Body Proportions and Final Height in X-Linked Hypophosphatemic Rickets
Status:
Unknown status
Trial end date:
2009-08-01
Target enrollment:
Participant gender:
Summary
X-linked hypophosphatemic rickets (XLH) is characterized by rickets, disproportionate short
stature, impaired renal phosphate reabsorption and vitamin D metabolism. Despite oral
phosphate and vitamin D treatment, most children with XLH demonstrate reduced adult height.
The main objective of the study is to determine the beneficial effects of recombinant human
growth hormone (rhGH) therapy on body proportions after 36 month in these patients. Secondary
objective is to monitor side effects of the therapy.