Effects of Fish Oils on Inflammation and Insulin Resistance

• Status: Completed
• Trial end date: 2015-01-15
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether improvement in fat and muscle metabolism after the treatment with Omacor (fish oils) provides insight into the link between obesity, fat and muscle function leading to metabolic syndrome, which is a risk factor for heart disease and diabetes.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Philip Kern
• Collaborators: GlaxoSmithKline; National Center for Research Resources (NCRR); National Institutes of Health (NIH)

Criteria

Inclusion Criteria:

• BMI 27-45 kg/m2

• age 35-65 years

• abnormal carbohydrate metabolism

Exclusion Criteria:

• triglycerides over 700 mg/dl

• renal disease

• liver disease

• congestive heart failure

• history of heart disease or stroke

• chronic aspirin or NSAID use (anti-coagulant)

• history of a bleeding disorder

• use of statins, fibrates, ACE inhibitors, angiotensin II receptor blockers and glucocorticoids

• diet heavy in omega-3 fatty acids (salmon, sardines, flaxseeds)