Overview

Effects of FXR Activation on Hepatic Lipid and Glucose Metabolism

Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether chenodeoxycholic acid decreases de novo hepatic lipogenesis, hepatic fat content, hepatic triglyceride production and plasma triglyceride concentrations and improves hepatic glucose metabolism in patients with the metabolic syndrome, Familial Hypertriglyceridemia and Familial Combined Hyperlipidemia.
Phase:
Early Phase 1
Details
Lead Sponsor:
University Hospital, Basel, Switzerland
Treatments:
Chenodeoxycholic Acid