Overview

Effects of Estrogen and Hot Flashes on Mood in Postmenopausal Women

Status:
Terminated
Trial end date:
2011-02-01
Target enrollment:
Participant gender:
Summary
This protocol is a controlled study of estradiol therapy in early postmenopausal women with and without frequent hot flashes that will be used to determine whether hot flashes are an important intermediary in the generation of menopause-associated depression.
Phase:
Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborator:
National Institutes of Health (NIH)
Treatments:
Estradiol
Estradiol 17 beta-cypionate
Estradiol 3-benzoate
Estradiol valerate
Estrogens
Polyestradiol phosphate