Effects of Electronic Cigarettes on Nicotine Concentrations

• Status: Completed
• Trial end date: 2015-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will examine whether nicotine levels increase with electronic cigarettes. It will also examine whether electronic cigarettes alter lung function tests. The study will obtain preliminary data on the medical effects of electronic cigarettes, with two different nicotine flavors, tobacco and tobacco with menthol, which are available for over the counter purchase.

The electronic cigarettes and juice used in this study is available for purchase through the internet. An investigational new drug application (IND) is not needed for this study.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: UConn Health
• Treatments: Menthol; Nicotine

Criteria

Inclusion Criteria:

• Smoking 10 cigarettes daily

• Agree to abstain from smoking and use electronic cigarettes for 2 weeks

Exclusion Criteria:

• Unstable medical or psychiatric disorders as determined by the principal investigator

• Pregnancy

• Known hypersensitivity to nicotine or propylene glycol or menthol

• Recent M. I. or stroke

• Uncontrolled hypertension (BP.>160/100)

• Insulin dependent diabetes

• Known COPD or asthma

• Alcohol or other drug abuse or dependence