Effects of Electrical Stimulation and Vitamin D Supplementation on Bone Health Following Spinal Cord Injury.
Status:
Recruiting
Trial end date:
2023-06-30
Target enrollment:
Participant gender:
Summary
Neurogenic osteoporosis is a common complication of spinal cord injury (SCI) that is
associated with low impact bone fractures. It is concerning that more than 46,000 Veterans
affected with SCI and are at risk of osteoporosis and possible low impact fractures. About
fifty percent of all individuals with SCI will develop low impact fracture in their life
time. The management of osteoporosis-related fractures can impose substantial economic burden
on the health care system, the individual and the families. Previous studies did not succeed
in reversing the process of bone loss after SCI. In the present pilot study, we will evaluate
the effect of Neuromuscular Electrical Stimulation Resistance Training in combination with
oral Vitamin D supplementation, on bone quality in Veterans with chronic SCI, using a
randomized experimental design.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
VA Office of Research and Development
Collaborators:
NYU Langone Health Virginia Commonwealth University