Effects of Dose and Injection Site for Gummy Smile Treatment With Botulinum Type A
Status:
Completed
Trial end date:
2020-06-20
Target enrollment:
Participant gender:
Summary
Botulinum type A (BTX-A) is an easy and efficacious treatment for gingival smile (GS).
However, its dosage and injection sites effect among patients are controversial.The objective
was to compare the reduction of gingival exposure using two methods in patients with
different dosage and injection sites. In this prospective self-controlled study, healthy GS
participates who had an anterior gingival exposure (GE) of more than 3 mm were enrolled and
administered single-point injection of 2 U BTX-A per side in the Simplified Method. And after
8 months, the Individualized Method was administered with 2-5 U BTX-A (total, 4-10 U)
injections into 1-2 points according to the severity presented pretreatment. Data were
collected at baseline and 4, 12, and 32 weeks of follow-up.