Effects of Different Kinds of Hypotensive Drugs on Dynamic Hemodynamic Changing in Patients Under Surgeries

• Status: Completed
• Trial end date: 2019-02-15
• Target enrollment: 0
• Participant gender: All

Summary

SVV is clinically affected by a variety of factors, such as abdominal pressure, body position, tidal volume, type and temperature of liquid treatment, etc. There are few reports on the effects of drugs on SVV.

In clinical anesthesia, surgical stimulation and stress can affect patient hemodynamic stability, used in intraoperative vascular active drug is inevitable, they shrink or dilate blood vessels, speed up or slow down the heart rate, makes the ventricular preload and corresponding changes in the SV. Now, there is a study on SVV and PPV in patients with hypertension, but there are few reports on the effect of blood pressure drugs on the changes in patients' threshold.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chinese PLA General Hospital
• Treatments: Nicardipine; Urapidil

Criteria

Inclusion Criteria:

1. ASA Ⅰ-Ⅲ

2. body mass index (BMI) 18-26kg/m2.

3. Hypertension and non-hypertensive patients

4. diabetic no complications

5. no lung, liver, kidney and blood system diseases

6. preoperative examination is basically normal.

Exclusion Criteria:

• Any type of arrhythmia, intraoperative need for other vasoactive drug intervention.