Effects of Dexmedetomidine on Cough Response and Postoperative Recovery Quality in Patients Undergoing Thyroid Surgery With General Anesthesia

• Status: Unknown status
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Coughing is a common adverse reaction of thyroid surgery,which could result in postoperative bleeding.Postoperative bleeding is a serious and potentially life-threatening complication，which could result in acute upper airway obstruction due to neck hematoma and increase the need for re-operation.The purpose of this study is to investigate whether dexmedetomidine can reduce the incidence of postoperative coughing and contribute to postoperative recovery in patients undergoing tyroid surgery with general anesthesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: First Affiliated Hospital of Chongqing Medical University
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

1. Aged from 18 to 65 years old

2. American Society of Anesthesiologists (ASA) physical statusⅠor Ⅱ

3. Diagnosed by B ultrasonic or tissue biopsy show that patients thyrophyma,thyroid cancer,thyroid nodule,etc,who need to accept thyroid surgery

Exclusion Criteria:

1. large goiter or hyperthyroidism

2. Preoperative coughing caused by primary diseases of patients

3. Ⅱdegrees above atrioventricular block

4. Allergy to anesthesia

5. History of diabetes

6. Pregnant women

7. Serious mental disease

8. History of alcohol or drug abuse

9. Severe heart renal or liver dysfunction

10. The presence of an upper respiratory infection

11. Asthma

12. Anticipated difficult airway