Effects of Dexmedetomidine on Breast Cancer Cell Function in Vitro
Status:
Completed
Trial end date:
2017-09-08
Target enrollment:
Participant gender:
Summary
Dexmedetomidine is widely used as an anaesthetic for general anesthesia during surgery.
Previous studies in cells and animals show that dexmedetomidine may promote cancer growth.
Using serum from breast cancer surgery patients randomized to receive dexmedetomidine or
saline during surgery, we investigated the effects of dexmedetomidine on proliferation,
migration and metastasis in MCF-7 breast cancer cells in vitro.