Effects of Denosumab on the Pharmacokinetics of Etanercept
Status:
Terminated
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
The primary objective of the study was to characterize the effects of a single dose of
denosumab on the pharmacokinetics (PK) of etanercept in postmenopausal women with low bone
mineral density (BMD) and rheumatoid arthritis based on area under the serum
concentration-time curve (AUC) and maximum observed serum concentration (Cmax).