Effects of Crofelemer on the Gut Microbiome in Healthy Volunteers and in HIV+ Patients With Non-Infectious Diarrhea
Status:
Completed
Trial end date:
2021-08-31
Target enrollment:
Participant gender:
Summary
This study is intended to evaluate:
1. Any changes in the gut microbiome from baseline compared to end of study in both healthy
(HIV-negative) subjects and HIV+ patients with or without chronic diarrhea, following
one month of treatment with crofelemer (Mytesi), delayed release 125 mg tablets twice
daily (BID) following one month of treatment.
2. The safety and tolerability of crofelemer, (Mytesi) delayed release 125 mg tablets BID
in healthy (HIV-negative) volunteers and HIV+ patients following one month of treatment.