Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training
Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
To determine, in a double blind trial, the effects of creatine supplementation during 12
weeks on muscle mass and function of community living older women subjected to resistance
training. Material and methods: Fifty healthy older women will be selected for the study. All
participants will be subjected to a progressive resistance training program using elastic
bands and weights, consisting in three sessions per week lasting 1 hour. Participant will be
randomly allocated in a double blind fashion, to receive creatine 5 g per day or an identical
placebo. The training and supplementation period will last 12 weeks. At baseline and at the
end of the study, body composition will be measured by dual energy x-ray absorptiometry,
rectus femoris cross sectional height and surface will be measured by ultrasound, quadriceps
strength will be measured in a quadriceps table and 12 minutes' walk will be assessed. The
main outcome measure will be quadriceps cross sectional height. Expected results: We expect
that creatine supplementation will increase rectus femoris height over and above the effect
of resistance training.