Effects of Carvedilol on Suppressing the Premature Ventricular Complex/Ventricular Tachycardia From Outflow Tract
Status:
Unknown status
Trial end date:
2020-12-31
Target enrollment:
Participant gender:
Summary
Carvedilol is known to be effective in reducing ventricular arrhythmias and mortality in
patients with heart failure. It is suggested that one of the mechanisms is its ability to
block store overload-induced Calcium release which activates spontaneous calcium release by
Ryanodine receptors. Ventricular outflow tract tachyarrhythmia is known to be associated with
calcium overload due to activation of Ryanodine receptors. The aim of this study is to
evaluate the efficacy of Carvedilol on premature ventricular complex(PVC)/ventricular
tachycardia(VT) originating from outflow tract.