Effects of Capsimax on Appetite, Energy Intake and Blood Pressure
Status:
Completed
Trial end date:
2019-07-02
Target enrollment:
Participant gender:
Summary
Obesity is an ongoing major public health problem in most countries of the world for which
the agrifood industry still remains criticized because of the abundant offer of high
sugar-lipid-energy dense foods, particularly in the fast-food sector. The resulting societal
pressure on the food industry probably explains in part the efforts that have been deployed
to seek natural active ingredients and to develop functional foods favorably influencing
energy balance. Capsaicin is a food non-nutrient constituent that was shown to decrease
appetite sensations and subsequent energy intake. The measurement of heart rate variability
revealed an association between the increase in sympathetic nervous system (SNS) activity and
the satiating effects induced by capsaicin. This is concordant with the observation that
pre-prandial intake of capsaicin, be it in capsules or diluted in tomato juice, increased
satiety and reduced energy intake.
The objective of this study is to evaluate the long effects of Capsimax on appetite
sensations and energy expenditure under conditions of moderate energy restriction and to
evaluate the long-term effects of Capsimax on energy intake and expenditure under conditions
of moderate energy restriction.