Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury
Status:
Active, not recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods
(termed intermittent hypoxia) is a safe and effective treatment strategy to promote
meaningful functional recovery in persons with chronic spinal cord injury (SCI). The goal of
the study is to understand how caffeine may augment the effects of intermittent hypoxia on
motor function and spinal plasticity (ability of the nervous system to strengthen neural
pathways based on new experiences) following SCI.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Spaulding Rehabilitation Hospital
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)