Dependence on heroin is a major public health problem because of its association with
criminality, law enforcement costs and healthcare costs. Managed withdrawal is a required
first step for a long term drug-free treatment of heroin addicts. Methadone and clonidine
have been the mainstay of treatment for the relief of heroin withdrawal symptoms but both
have limitations. The purpose of this study was to evaluate the efficacy of buspirone in the
alleviation of the withdrawal symptoms experienced by heroin addicts when they stop using
heroin. Buspirone is a non opiate drug with no abuse potential, no sedating effects and no
withdrawal symptoms.