Bosentan has been largely used in the treatment of pulmonary hypertension (PH). It can
improve exercise capacity, lower Borg dyspnoea score nad these effects are usually associated
with the concomitant improvement in cardiopulmonary haemodynamics.
No physiological study has so far verified the hypothesis that Bosentan may laso have an
effect on the "respiratory side" of the cadio-pulmonary system (i.e. on pulmonary mechanics
and work of breathing)
Phase:
Phase 4
Details
Lead Sponsor:
Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi IRCCS Azienda Ospedaliero-Universitaria di Bologna