Overview

Effects of Bioflavanoids on Vascular Wall Remodeling in Patients With Varicose Veins

Status:
ACTIVE_NOT_RECRUITING
Trial end date:
2026-05-01
Target enrollment:
Participant gender:
Summary
The study is aimed at assessing the dynamics of changes in biochemical markers of venous wall remodeling (type 1 plasminogen activation inhibitor (PAI-1), fibronectin (fibronectin, FN), vimentin (vimentin, VM), von Willebrand factor (vWF), PECAM-1 (CD31) ) in patients with C2s-C3s varicose veins compared with healthy volunteers while taking VenarusĀ® (diosmin in combination with hesperidin).
Phase:
NA
Details
Lead Sponsor:
Ryazan State Medical University
Treatments:
Diosmin
Fibronectins
Flavonoids
Hesperidin
Plasminogen Activator Inhibitor 1
Platelet Endothelial Cell Adhesion Molecule-1
Vimentin