Effects of Baclofen on Presynaptic Inhibition in Humans
Status:
Recruiting
Trial end date:
2021-01-10
Target enrollment:
Participant gender:
Summary
This study examines the role of the GABA-B receptor in long-lasting presynaptic inhibition of
primary afferents in human participants. Participants will come in for two visits, receiving
baclofen (a GABA-B receptor agonist) on one visit and a placebo during the other.
Electro-physiological measures will be use during both visit to asses presynaptic inhibition.