Effects of Atorvastatin on Human Semen and Gonadal Hormones
Status:
Completed
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
Recently, concerns about the effect of atorvastatin intake on men fertility have been raised.
However, this statin has never been investigated regarding its influence on male fertility,
notably sperm quality.
The aim of this pilot study is to evaluate the efficacy and the safety of a decrease of
cholesterol blood levels, induced by taking atorvastatin, on sperm quality of
normocholesterolaemic and healthy men without confounding factors.
Phase:
Phase 1
Details
Lead Sponsor:
University Hospital, Clermont-Ferrand
Collaborators:
EA 975, Laboratoire de BDR Laboratoire d'Hormonologie - Biochimie Laboratoire d’Hormonologie - Biochimie Service d'Endocrinologie, Diabète et Maladies Métaboliques Service d’Endocrinologie, Diabète et Maladies Métaboliques Service de Biologie de la Reproduction : AMP-CECOS