Effects of Angiotensin Receptor Antagonist on Prohibiting Cardiovascular Events on Hemodialysis Patients

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Cardiovascular disease is a leading cause of mortality in patients on hemodialysis therapy (HD), accounting for 30 to 50% of all death. Although angiotensin receptor blockers (ARBs) are effective for patients with diabetes and chronic kidney disease in reducing or preventing cardiovascular diseases, there has been no decisive study that demonstrated treatment with ARBs is effective in patients on HD.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Saitama Medical University
• Treatments: Angiotensin Receptor Antagonists; Candesartan; Losartan; Valsartan

Criteria

Inclusion Criteria:

• 30 to 80 years of age

• Receiving hemodialysis at least 12 months and less than 5 years

• Pre-dialysis systolic blood pressure was more than 160 mmHg, or more than 150 mmHg if the patients received antihypertensive agents.

Exclusion Criteria:

• Use of angiotensin receptor blocker or angiotensin converting enzyme inhibitor