undertake confidently both open and laparoscopic cholecystectomy. Major types of body
injuries surgical or accidental; evoke a temporary, yet predictable systemic inflammatory
response caused by hormonal, immunological and metabolic mediators. This inflammatory
response is essential for tissue repair and has evolved to maximize the organisms' healing
potential. In healthy individuals the inflammatory response to major surgery is well balanced
consisting of pro- and anti-inflammatory mediators. The severity of injury, the occurrence of
surgical complications and its accompanying level of stress may hinder the balance of the
inflammatory response6.