Effects of Amlodipine in the Management of Chronic Heart Failure
Status:
Terminated
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Patients with congestive heart failure are usually treated with a combination of an ACE
inhibitor (or an AT1 blocking agent), a diuretic and a beta-blocker. However, some patients
remain symptomatic despite an optimal treatment with these drugs. In patients who also have
coronary heart disease, nitrates or some calcium-channel blockers could help to relieve
symptoms. Therefore, the aim of our study is to evaluate the additional benefit induced by a
second generation calcium-channel blocker, amlodipine, in patients with chronic heart failure
who remain symptomatic despite an optimal treatment.