Effects of Amitriptyline for the Treatment of Pain on Driving Performance and Cognition.
Status:
Terminated
Trial end date:
2005-05-01
Target enrollment:
Participant gender:
Summary
The acute and subchronic effects of amitriptyline were compared to placebo in a double-blind
crossover randomized study on driving ability and driving-related skills in chronic
neuropathic pain patients.It was hypothesized that nocturnally administered 25 mg
amitriptyline might affect driving performance negatively after acute, but not after
subchronic treatment.
Phase:
Phase 4
Details
Lead Sponsor:
UMC Utrecht
Collaborator:
Utrecht University
Treatments:
Amitriptyline Amitriptyline, perphenazine drug combination