Overview

Effects of 4-AP on Functional SCI Recovery

Status:
Recruiting
Trial end date:
2025-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test a strategy to potentiate functional recovery of lower limb motor function in individuals with spinal cord injury (SCI). The FDA approved drug, Dalfampridine (4-AP). 4-AP will be used in combination of Spike-timing-dependent plasticity (STDP) stimulation and STDP stimulation with limb training.
Phase:
Early Phase 1
Details
Lead Sponsor:
Shirley Ryan AbilityLab
Collaborator:
National Institute of Neurological Disorders and Stroke (NINDS)
Treatments:
4-Aminopyridine