Effects of 3% Sodium Chloride on Post-operative Dysphagia Following Anterior Cervical Spine Surgery

• Status: Withdrawn
• Trial end date: 2019-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Post-operative dysphagia is a significant issue following anterior cervical spine surgery. The investigators are studying the effects of perioperative 3% sodium chloride, given over a period of 24 hours, on post-operative dysphagia. The goal is to reduce the incidence and severity of post-operative dysphagia.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Missouri-Columbia

Criteria

Inclusion Criteria:

• Adult patients undergoing anterior cervical discectomy and fusion for degenerative indications

Exclusion Criteria:

• history of cervical trauma

• baseline dysphagia

• age less than 18 years old

• history of previous anterior neck surgery

• Creatinine clearance less than 30

• Creatinine greater than 1.0

• baseline sodium greater than 145

• patients with known electrolyte abnormalities

• congestive heart failure