Effects and Safety of Clonidine Patch on Young and Middle-aged Smokers With Mild Hypertension
Status:
Not yet recruiting
Trial end date:
2025-08-01
Target enrollment:
Participant gender:
Summary
The optimal antihypertensive treatment strategy in young and middle-aged hypertensive adults
remains undefined. Clonidine controlled-release patches administered once a week might have
the advantage of convenience. ECLIPSE trial is intended to observe the effect and patient
tolerability of clonidine controlled-release patches (one patch per week for a total of 8
weeks) in the treatment of hypertension in young and middle-aged adults, compared with
long-acting antihypertensive drug amlodipine. Clonidine patch was demonstrated ameliorating
the early withdrawal symptoms during smoking cessation. This trial is also intended to
observe its effect on smoking cessation in young and middle-aged male smokers.