Overview

Effects Of The Drug Ketoconazole On How The Body Handles The Drug SB773812

Status:
Completed
Trial end date:
2007-10-10
Target enrollment:
0
Participant gender:
Male
Summary
The purposes of this study are to determine if there is a difference in how SB-773812 is distributed through the bloodstream before and after multiple doses of ketoconazole have been given and to determine if there is a difference in how safe and well tolerated SB-773812 is when given on its own and given with ketoconazole.
Phase:
Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
GlaxoSmithKline
Treatments:
Ketoconazole
Criteria
Inclusion criteria:

- Healthy

- Body Weight >/=50kg and BMI 18.5-29.9 kg/m2 inclusive

- Normal 12-lead ECG, physical examination and lab screen

Exclusion criteria:

- A history of psychiatric illness,

- A history or presence gastro-intestinal,

- A hepatic or renal disease or orthostatic hypotension.