Effectiveness of the Nicotine Patch in Suppressing Nicotine Withdrawal Symptoms in Women Versus Men - 1

• Status: Completed
• Trial end date: 2005-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Women typically have a more difficult time quitting smoking than men. Little research has been done to understand the differences between men and women that may cause this distinction. This study will assess whether the reduced effectiveness of nicotine replacement therapy in women is caused by gender differences in the withdrawal suppression induced by nicotine replacement therapy.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• Smokes at least 15 cigarettes a day for at least 2 years prior to enrollment

• Has an afternoon carbon monoxide level of at least 15 ppm

• Agree to use an effective form of contraception for the duration of the study

Exclusion Criteria:

• History of chronic health problems

• History of psychiatric conditions

• History of or active cardiovascular disease

• History of or active high or low blood pressure

• History of or active seizure condition

• History of or active peptic ulcers

• History of or active diabetes

• Pregnant

• Score of greater than 17 on the Beck Depression Inventory