Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates

• Status: Recruiting
• Trial end date: 2021-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary aim of the work is to compare the efficacy of Sugammadex and neostigmine in reversing rocuronium-induced muscle relaxation to reach complete recovery of neuromuscular block (TOF ratio≥ 0.9) in preterm neonates.

The secondary aim is to evaluate the safety of using Sugammadex in preterm neonates and to detect any complications that may occur in this age group.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alexandria University
• Treatments: Neostigmine

Criteria

Inclusion Criteria:

• preterm neonates

• scheduled for elective inguinal hernia repair

Exclusion Criteria:

• drug hypersensitivity

• patient is with any diseases affecting the neuromuscular junction

• Patients with family history of malignant hyperthermia