Effectiveness of Platelet Rich Plasma in Wound Healing
Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
Purpose: This prospective randomized comparative clinical study was conducted to assess the
effect of platelet-rich plasma (PRP) gel on soft tissue healing and bone regeneration
potential on lower third molar extraction sockets.
Methods: For the study, 50 Patients (37 male, 13 female) requiring surgical removal of a
lower impacted third molar and who fulfilled the inclusion criteria were recruited. The
patients were categorized into two groups, Group A and Group B. For each group 25 patients
were randomly allocated. The predictor variable in Group A was the application of PRP Gel
whereas in Group B had no PRP. Postoperative pain, swelling, trismus, soft tissue healing and
osseous regeneration was assessed using standard methods. These outcome variables were
assessed on 1, 3-, 5-, 7-, and 14-postoperative day. Patients were recalled at the 4th, 10th,
and 16th postoperative week for assessment of bone healing. The data were recorded and
tabulated.