Effectiveness of Metformin in Recurrent Miscarriage in a Woman With Hyperinsulinaemia
Status:
Withdrawn
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
The prevalence of insulin resistance is increased in women with recurrent miscarriage
compared with matched fertile controls,Insulin resistance (IR) in this syndrome is not only
implicated toward early pregnancy loss (EPL) but also pathognomic for various obstetrical
complications during pregnancy.An elevated free androgen index appears to be a prognostic
factor for a subsequent miscarriage in women with recurrent miscarriage.
There is insufficient evidence to evaluate the effect of metformin supplementation in
pregnancy to prevent a miscarriage in women with recurrent miscarriage.