Overview

Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes

Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
0
Participant gender:
All
Summary
This will be a double-blind placebo-controlled study in which we plan to study 40 competitive endurance athletes. We will conduct an exercise test to evaluate maximal oxygen uptake and 2 exercise challenge tests to provoke EIA. Prior to the exercise challenge tests the athletes will randomly receive inhaled placebo or inhaled ipratropium bromide. We will compare the athletes' airway response to the exercise challenge with and without the active drug.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of California, San Francisco
Treatments:
Bromides
Ipratropium
Criteria
Inclusion Criteria:

- Athletes > 13 years of age

Exclusion Criteria:

- History of cardiac complaints (chest pain, shortness of breath, palpitations, dyspnea
on exertion).

- History of cardiac disease or taking cardioactive medications.

- History of smoking.

- History of glaucoma.