Effectiveness of Individualized Homeopathic Treatment in Perennial Allergic Rhinitis
Status:
Completed
Trial end date:
2006-12-01
Target enrollment:
Participant gender:
Summary
A total of 41 adults with perennial allergic rhinitis were enrolled in a first double-blind
placebo-controlled phase for six months, and treated on a weekly basis with sublingual doses
of single individualized homeopathic medicines or placebo. After this closed initial phase,
all patients were invited to participate in an long-term open-label controlled phase, in that
they would receive homeopathic treatment for the maximum period of 36 months, and the results
were compared with the improvement of initial phase. Signs and symptoms scores, rescue
medication requirements and quality of life were assessed by questionnaires and personal
clinical evaluation by a same independent researcher, before and after each phase. Primary
and secondary clinical outcome were, respectively, specific and general allergic signs and
symptoms scores. Total IgE titles were performed before and after each phase.