Effectiveness of Buspirone and Motivational Enhancement Therapy for the Treatment of Marijuana Dependence - 1

• Status: Completed
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will assess the effectiveness of a combination of buspirone and motivational interviewing therapy in the treatment of marijuana dependence.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of South Carolina
• Collaborator: National Institute on Drug Abuse (NIDA)
• Treatments: Buspirone

Criteria

Inclusion Criteria:

• Meets DSM-IV criteria for marijuana dependence

• Lives within 60 miles of the study site

• Willing to provide collateral individuals for contact purposes

• Willing to use an effective form of contraception throughout the study

Exclusion Criteria:

• Meets DSM-IV criteria for dependence upon a substance other than marijuana, nicotine, or caffeine

• Meets DSM-IV criteria for a history of schizophrenia or another non-affective psychotic disorder or bipolar disorder

• Meets DSM-IV criteria for current major depressive disorder or eating disorder

• Significant cognitive impairment

• Currently taking benzodiazepines, antidepressant, or antipsychotic medications

• Major medical illnesses (e.g., HIV, kidney failure, unstable angina, chronic obstructive pulmonary disease, infectious hepatitis)

• Not in stable housing

• Pregnant or breastfeeding