Effectiveness of BBT-I and Zopiclone for Chronic Insomnia
Status:
Completed
Trial end date:
2017-03-14
Target enrollment:
Participant gender:
Summary
Background: Importance of chronic insomnia (CI) problem is determined by its high prevalence
rate, comorbidity and resistance to the treatment. Although cognitive behavior treatment of
insomnia (CBT-I) remains the recommended treatment for CI it has disadvantages of time
consuming and low treatment response. Hence shortened and simplified behavioral approaches
such as Brief Behavioral therapy of insomnia (BBT-I) are developed. The aim of the present
study is to test the effectiveness of BBT-I program for chronic insomnia in comparison with
zopiclone in Russian population. The anthropometric, psychological and polysomnographic
characteristics of patients were measured to find predictors of effectiveness of each method.
Participants: 42 adults (14 males, 28 females, mean age 54 years) meeting the criteria for CI
according International classification of sleep disorders-3 Methods: Participants were
randomized into two groups. Each group passed 2-week courses of treatment by brief behavior
treatment of insomnia (BBT-I) and zopiclone in different orders with 2-week washout period
between the courses. Participants underwent in-lab polysomnography prior to the treatment and
completed questionnaires (Insomnia Severity Index (ISI), Dysfunctional beliefs about sleep
scale (DBAS), Beck Depression Inventory (BDI) and others) in the beginning and the end of
each course
Phase:
Phase 2
Details
Lead Sponsor:
I.M. Sechenov First Moscow State Medical University