Overview

Effectiveness of Antitussives, Anticholinergics and Honey Versus Usual Care in Adults With Acute Bronchitis.

Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
This study, which is aimed at comparing the effectiveness of 3 symptomatic therapies (dextromethorphan, ipratropium and honey) associated with usual care and the usual care in adults with acute bronchitis, is a multicentre, pragmatic, parallel group, open randomised trial. Patients aged 18 or over with uncomplicated acute bronchitis, with cough <3 weeks as the main symptom, scoring ≥ 4 in either daytime or nocturnal cough on a 7-point Likert scale, will be randomised to one of the 4 groups. Sample: 668 patients. The primary outcome will be the number of days with moderate-severe cough.
Phase:
Phase 4
Details
Lead Sponsor:
Jordi Gol i Gurina Foundation
Collaborators:
Spanish Clinical Research Network - CAIBER
Spanish Clinical Research Network - SCReN
Treatments:
Antitussive Agents
Bromides
Chlorpheniramine, phenylpropanolamine drug combination
Cholinergic Antagonists
Dextromethorphan
Guaifenesin
Ipratropium
Phenylpropanolamine