Effectiveness of AZT and Nevirapine in Preventing HIV Transmission From Ugandan Mothers to Their Newborns
Status:
Completed
Trial end date:
2004-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to see if nevirapine (NVP) or zidovudine (AZT), given to mothers
during labor and delivery and to their babies during the first week of life, can reduce the
rate of mothers passing HIV to their babies.
About 25 percent of HIV-infected mothers pass HIV infection to their babies during labor and
delivery. There is an urgent need to find a simpler way to prevent mother-to-infant
transmission during labor and delivery. The proposed NVP schedule is simpler and possibly
could be used in Uganda.
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)