Overview

Effectiveness and Safety of Timolol and Dorzolamide Loaded Contact Lenses

Status:
Recruiting
Trial end date:
2021-11-01
Target enrollment:
Participant gender:
Summary
This study focuses on glaucoma therapy by drug eluting contact lenses. The contact lens will be loaded with timolol maleate and dorzolamide hydrochloride, both of which are commonly used ophthalmic drugs. Additionally, the lenses will contain vitamin E ((+) α-tocopherol) as an additive for achieving extended release of the drugs. This study is to assess the safety of the drug loaded contact lenses and the effectiveness. Effectiveness will be a drop in IOP after using the lenses.
Phase:
Phase 1
Details
Lead Sponsor:
University of Florida
Treatments:
Dorzolamide
Maleic acid
Timolol