Effectiveness Silver Diamine Fluoride Versus Sodium Fluoride in Arresting Caries Around Crown Margins in Older Adults

• Status: Recruiting
• Trial end date: 2024-01-03
• Target enrollment: 0
• Participant gender: All

Summary

Dental caries is a multifactorial, progressive disease which is the major causes of dental pain, infection and tooth loss. Dental caries can substantially compromise the quality of life in older adults 1 2. As the number of older adults in the US increases, the dental professionals have become increasingly concerned with the dental need of elderly and preventive regimes to reduce the incidence of caries3 .

Prevention becomes an area of paramount importance. Many studies have advocated nonsurgical intervention for shallow dentin caries lesion.The most effective method for prevention to date is considered to be fluoride. In the United states fluoride has been incorporated in many ways like water fluoridation, fluoride mouth wash, dentifrices and professionally applied fluoride varnishes . The American Dental Association (ADA) recommended the use of fluoride for patients of all ages who are at risk of developing dental caries7 . With the high success of fluoride, another treatment method using Silver Diamine Fluoride (SDF) is gaining popularity in the United States. SDF has been used in many countries like Japan, Australia, China, and Cuba for treatment of caries . Successful treatment data from other countries is promising, and promoting the use of SDF in the United States. SDF is available in the United States as 38% aqueous solution and approved as a desensitizing agent. American Dental Association published an evidence-based clinical practice guideline on nonrestorative treatments for caries teeth and recommended use of SDF on a carious cavitated lesion on permanent teeth9 . Clinical studies have shown the effectiveness of SDF in arresting root caries in older adults.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of New England
• Treatments: Fluorides; Fluorides, Topical; Listerine; Sodium Fluoride

Criteria

Inclusion Criteria:

• 65-85 years old with crown/bridges

• Open crown margins

• Decay present around crown margins

• Pt is not intention to go with the conventiontial restorative treatment to replace the crown for any reason

• Subjects who can do the follow up for at least one year

Exclusion Criteria:

• Teeth with periapical lesion

• Teeth which have pain to percussion

• Subjects who have silver or fluoride allergy

• Subjects who have gingivitis

• Subjects who have stomatitis

• Subjects who have tooth mobility

• Subjects who have furcation involvement