Effect of the Known Antihypertensive Drug Telmisartan on Red Blood Cells and Circulation in the Smallest Blood Vessels
Status:
Terminated
Trial end date:
2009-01-01
Target enrollment:
Participant gender:
Summary
The hypothesis of the presented study is: Telmisartan induces an increase of eNOS activity in
RBC resulting in an enhanced intravascular NO bioavailability, an ameliorated RBC
deformability and a reduction of RBC and platelet aggregation. This could be a potential
mechanism of the improvement of microcirculatory disorders, especially in patients with
diabetes mellitus and arterial hypertension, treated with Telmisartan.