Effect of an Inhibitor of Cholesterol Absorption on Vitamin D Levels

• Status: Completed
• Trial end date: 2015-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Double-blind randomized controlled trial to evaluate the serum levels of 25(OH)D after a single oral dose of cholecalciferol 50,000 IU plus ezetimibe or placebo.

Differences between the serum levels of 25(OH)D in response to cholecalciferol plus ezetimibe compared to cholecalciferol plus placebo.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Federal University of Rio Grande do Sul
• Treatments: Cholecalciferol; Ergocalciferols; Ezetimibe; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Medical students of the HCPA

Exclusion Criteria:

• Body mass index >+ 25 or < 18.5 kg/m2

• Known liver, kidney or endocrine disease

• Known malabsorption

• Use of supplements of calcium and/or vitamin Danticonvulsants, barbiturates, or glucocorticoids

• Travel outside the Brazilian south region during the previous 120 days